General Cell Lines and Cell Cultures
Revvity Health Sciences Inc AequoZen Human Lysophospholipid S1P5 (EDG5) Cell Line, CHO-K1 Frozen Cells
AequoZen Human Lysophospholipid S1P5 (EDG5) Cell Line, CHO-K1 Frozen Cells
Eurofins Discoverx Ready-to-Assay EP2 Prostanoid Receptor Frozen Cells, 2 Vials of Cells. (HTS185RTA)
The Ready-to-Assay EP2 Prostanoid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. prostaglandin E2) based activation of PTGER2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER2 alongside exogenous levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of PTGER2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx cAMP Hunter CHO-K1 OPRM1 Gi Cell Line, 2 vials. (95-0107C2)
The cAMP Hunter OPRM1 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. met-enkephalin, morphine) based activation of OPRM1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type OPRM1, a naturally Gi/Go coupled GPCR. Upon activation of OPRM1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Cell Applications Inc Human Aortic Smooth Muscle Cells Total Kit, Pooled, adult
Human Aortic Smooth Muscle Cells Total Kit, Pooled, adult(354p-05a) Cryopreserved (HAOSMC) 1 vial, pooled, adult(311-500) Smooth Muscle Cell Growth Media, 500ml(090K) Subculture Reagent Kit
Biochain Institute Inc Lung Tumor and Normal Tissue Array 60 spots: Duplicated spots from lung tumor tissues (25 donors) and lung normal tiss, 5 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Postcentral Gyrus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Paraffin Tissue Section - Human Kidney Tumor: Clear cell carcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC SCC-15; Tongue Carcinoma; Human (Homo Sapiens)
SCC-15 is a cell line that was isolated from the tongue of a 55-year-old, male patient with squamous cell carcinoma. This cell line was deposited by JG Rheinwald and can be used in cancer research.
Lonza Walkersville NHEK-Neo – Human Epidermal Keratinocytes – Neonatal, Single Donor
Cryopreserved Normal Human Epidermal Keratinocytes Neonatal are guaranteed through 18 population doublings for adult cells. All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased. Benefits:Assured for experimental use up to 20 population doublings All cells test negative for mycoplasma, bacteria, yeast, and fungiHIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lotsCharacterized by morphological observation throughout serial passageCertificate of Analysis is provided for each cell lotApplications:Skin modelingOncologyProtective barrierWound healingPigmentation Content:1 x Cryopreserved ampule of NHEK-Neo (single donor) containing ≥ 500,000 cells
Medchemexpress LLC GLP1R protein, human (HEK293, N-His, C-Myc) | >95.0% | 100UG
Recombinant human GLP1R protein expressed in HEK293 cells and supplied lyophilized with N-terminal His and C-terminal C-Myc tags. The glycosylated receptor is functional in ligand-binding assays, activates adenylyl cyclase to increase intracellular cAMP upon ligand binding, and is suitable for biochemical characterization, antibody validation, and receptor-ligand interaction studies.
- Expressed in HEK293 cells.
- N-His and C-Myc tagged for detection and purification.
- Glycosylated; apparent molecular weight ~25-38 kDa.
- Purity >95% by reducing SDS-PAGE.
- Available in 20 μg, 50 μg, and 100 μg quantities.
- Lyophilized formulation with trehalose for stability.
- Store at -20°C; reconstituted material stable at 4°C for one week.