General Cell Lines and Cell Cultures
Lonza Walkersville OBM Osteoblast Growth and Dif
OBM is an osteoblast cell growth basal medium sold separately This can be used with 1 kit of CC-4193 (osteoblast growth medium SingleQuots Supplements and Growth Factors) The full OGM BulletKit consisting of basal medium and supplements can be purchased together using the catalog number CC-3207 Clonetics OGM Osteoblast Growth Medium is specially formulated for the growth and expansion of human osteoblasts The kit contains 10% serum OGM Differentiation Supplements are also included and are recommended for use with differentiation assays The kit is conveniently packaged to include basal medium with growth and differentiation supplements for complete culture of osteoblasts
Eurofins Discoverx PathHunter CHO-K1 PTGIR β-Arrestin Cell Line, 2 vials. (93-0305C2)
The PathHunter PTGIR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin I2, beraprost) based activation of PTGIR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PTGIR and EA-tagged β-Arrestin-2. Activation of PTGIR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS TrkB Functional Assay, 2 vials. (93-0463C3)
The PathHunter U2OS TrkB Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TrkB dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TrkB and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx PathHunter U2OS TBXA2R β-Arrestin Cell Line, 2 vials. (93-0322C3)
The PathHunter TBXA2R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. thromboxane A2, prostaglandins) based activation of TBXA2R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TBXA2R and EA-tagged β-Arrestin-2. Activation of TBXA2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter HEK 293 GPR152 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0384C1A)
The PathHunter GPR152 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR152 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR152 and EA-tagged β-Arrestin-2. Activation of GPR152 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter C2C12 CXCR5 β-Arrestin Cell Line, 2 vials. (93-0204C7)
The PathHunter CXCR5 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. [ligand]) based activation of CXCR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR5 and EA-tagged β-Arrestin-2. Activation of CXCR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter HEK 293 CXCR6 β-Arrestin Cell Line, 2 vials. (93-0205C1)
The PathHunter CXCR6 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL16) based activation of CXCR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR6 and EA-tagged β-Arrestin-2. Activation of CXCR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter HEK 293 CCR2 β-Arrestin Cell Line, 2 vials. (93-0192C1)
The PathHunter CCR2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL2/MCP-1) based activation of CCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR2 and EA-tagged β-Arrestin-2. Activation of CCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.